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A total of 13 subjects on REMINYL (n=1026) and 1 subject on placebo (n=1022) died. However, there are several medications now available, including Aricept, Razadyne (formerly Reminyl), and Namenda, which can improve cognitive and behavioral symptoms. About half of the REMINYL deaths appeared to result from various vascular causes (myocardial infarction, stroke), and sudden death. These reports include instances in which Reminyl was prescribed but Amaryl was incorrectly dispensed and administered instead, leading to various adverse events including severe hypoglycemia and one death. These include four acetylcholinesterase inhibitors -- donepezil (Aricept), galantamine (Razadyne, Reminyl, Nivalin), rivastigmine (Exelon), and tacrine -- and one neuropeptide-modifying agent -- memantine (Mamenda). If treatment with Reminyl is interrupted for several days or longer, the patient will need to start over again at the lowest dose, increasing the dose at 4-week intervals until the former dose is achieved.
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